Effects of a Feedback-Resistant Aspartokinase III Gene onL-Isoleucine Production inEscherichia coliK-12
نویسندگان
چکیده
منابع مشابه
Mutation Analysis of the Feedback of Escherichia coli K・t 12 and its UseInhibition Site of Aspartokinase in L - Threoni e Production JSBA III Yuri OGAwA - MiyATA
Aspartokinase III (AKIII), one of three isozymes of EScherichia coti K-12, is iilhibited al]esterically by L-lysine. This enzyme is encoded by the lysC gene and has 449 amino acid residues. We analyzed the feedback inhibition site of AKIII by generating yarious 4)ngC mutants in a plasmid yector. These mutants conferred resistance to L-lysine and!or an L-lysine analogue on their host. The inhibi...
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ژورنال
عنوان ژورنال: Bioscience, Biotechnology, and Biochemistry
سال: 1999
ISSN: 0916-8451,1347-6947
DOI: 10.1271/bbb.63.2023